Recent advances in bone marrow biopsy pathology

Recent advances in bone marrow biopsy pathology

The second quarter of 2009 saw steady advances in bone marrow biopsy (BMB) pathology. The following publications are a personal selection of the highlights. Quality issues in diagnostic immunohistochemistry for BMB have largely been ignored in external quality assurance programmes, and this issue is highlighted. In other areas, publications reflecting advances in flow cytometry and aspirate mor...

The Role of Bone Marrow Aspiration and Bone Marrow Biopsy in Diagnosis of Bone Marrow Metastases

Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...

Highlights of 2008 in bone marrow biopsy pathology

The fiftieth anniversary of Blood saw the publication of a series of excellent review articles. The myeloproliferative disorders [1] were first characterised by Gustav Heuck who described myelofibrosis (MF) in 1879. Louis Henri Vaquez described polycythemia vera (PV) in 1892. Essential thrombocythemia (ET) followed somewhat later in 1934 when Emil Epstein and Alfred Goedel recognised it as a di...

Pitfalls in bone marrow pathology: avoiding errors in bone marrow trephine biopsy diagnosis.

Avoiding errors in the histological interpretation of bone marrow trephine biopsy specimens requires an unprecedented degree of collaboration between histopathologists, haematologists, specimen requesters, specimen takers, laboratory technical staff and other scientific staff. A specimen of good quality, with full, relevant clinical information is the essential starting point. This must then be...

Recent Advances in Pathology